1,2-diphenylpyrrole derivatives, their preparation and their...

Details 1,2-diphenylpyrrole derivatives, their preparation and their... 1,2-diphenylpyrrole derivatives, their preparation and their...

C - Chemistry, Metallurgy

07

D

C07D 207/30 (2006.01) A61K 31/40 (2006.01) C07D 207/325 (2006.01) C07D 207/333 (2006.01) C07D 405/02 (2006.01)

Patent

CA 2201812

Compounds of formula (I) and (II): (see formula I and II) [wherein R is hydrogen, halogen or alkyl; R1 is alkyl, amino or substituted amino; R2 is optionally substituted phenyl; R3 is hydrogen, halogen or optionally substituted alkyl; R4 is hydrogen, optionally substituted alkyl, cycloalkyl, aryl, or aralkyl] have valuable analgesic, anti-inflammatory, anti-pyretic and anti- allergic activities and have the ability to inhibit the production of leukotrienes and to inhibit bone resorption. They are relatively free from the side effects which generally result from the administration of compounds having these kinds of activities.

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