1,2-disubstituted aromatic chelates

Details 1,2-disubstituted aromatic chelates 1,2-disubstituted aromatic chelates

C - Chemistry, Metallurgy

07

F

C07F 3/00 (2006.01) A61K 31/11 (2006.01) A61K 31/19 (2006.01) A61K 31/28 (2006.01) C07C 43/23 (2006.01) C07C 45/77 (2006.01) C07C 47/58 (2006.01) C07C 49/92 (2006.01) C07C 51/41 (2006.01) C07F 11/00 (2006.01) C07F 13/00 (2006.01) C07F 15/00 (2006.01)

Patent

CA 2197883

Mineral absorption is promoted in warm-blooded animals by means of a class of 1,2-disubstituted aromatic mineral chelates wherein the 1 and 2 substituents each donates a pair of electrons to a metal ion for formation of a five-member chelate ring. 2-Alkoxyphenols are particularly preferred. The chelates contain from one to three alkoxyphenol ligands, with two ligands being preferred. A preferred alkoxyphenol is vanillin, and the minerals are selected from the group consisting of Mg, Ca, Cr, Mn, Fe, Co, Cu, Zn, Mo and Se. Vanillin metal chelates have a slight to neutral taste, and are absorbed more readily than inorganic mineral salts.

Chez les animaux à sang chaud, l'absorption des minéraux est favorisée par une classe de chélates aromatiques minéraux disubstitués en 1 et 2, dans lesquels les substituants en 1 et 2 cèdent chacun une paire d'électrons à un ion métallique de façon à former un noyau chélaté à 5 éléments. Les 2-alcoxyphénols bénéficient d'une préférence particulière. Lesdits chélates contiennent un à trois ligands alcoxyphénols, et de préférence deux. L'un des alcoxyphénols préférés est la vanilline, et les minéraux sont choisis parmi Mg, Ca, Cr, Mn, Fe, Co, Cu, Zn, Mo et Se. Les chélates métalliques de vanilline ont une saveur légère ou neutre et sont absorbés plus facilement que les sels minéraux non organiques.

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