1-¬2-(hydroxymethyl)cycloalkylmethyl|-5-substituted uracils

C - Chemistry – Metallurgy – 07 – D

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C07D 239/54 (2006.01) A61K 31/505 (2006.01) C07D 239/553 (2006.01)

Patent

CA 1293972

TITLE OF INVENTION 1-[2-(HYDROXYMETHYL)CYCLOALKYLMETHYL]-5-SUB- STITUTED URACILS ABSTRACT OF DISCLOSURE 1-[2-(Hydroxymethyl)cycloalkylmethyl]-5- substituted uracils which are herpes simplex viral thymidine kinase inhibitors, their acyl derivatives, and their pharmaceutically-acceptable salts; pharmaceutical formulations containing these compounds; the treatment of DNA viral, particularly herpes viral, infections with these compounds; methods of preparing these compounds; and novel intermediates useful in their preparation.

566441

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