1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives

Details 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives

C - Chemistry, Metallurgy

07

C

C07C 401/00 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2199893

The invention relates to a compound of the formula SEE FORMULA I wherein R is hydroxy and R1 is H2 or CH2, or R is hydrogen or fluoro and RI is CH2. Compounds of formula I are useful as agents for the treatment of hyperproliferative skin diseases, such as psoriasis, neoplastic diseases, such as leukemia, and sebaceous gland diseases, such as acne and sebhorreic dermatitis.

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