1,3-benzodiazepin-2-ones and 1,3-benzoxazepin-2-ones useful...

Details 1,3-benzodiazepin-2-ones and 1,3-benzoxazepin-2-ones useful... 1,3-benzodiazepin-2-ones and 1,3-benzoxazepin-2-ones useful...

C - Chemistry, Metallurgy

07

D

C07D 243/04 (2006.01) A61K 31/551 (2006.01) A61K 31/553 (2006.01) A61K 31/554 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01) A61P 37/04 (2006.01) A61P 43/00 (2006.01) C07D 267/06 (2006.01) C07D 281/02 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2330110

The present invention relates to 1,3-benzodiazepin-2-ones and 1,3-benzoxazepin- 2-ones of formula (I) or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

La présente invention concerne des 1,3-benzodiazépin-2-ones, et des 1,3-benzoxazépin-2-ones de formule (I), ou des formes stéréoisomères, des mélanges stéréoisomères, ou des formes salines pharmaceutiquement acceptables de celles-ci, qui peuvent être utilisées comme inhibiteurs de la reverse-transcriptase du VIH. Cette invention concerne également des compositions pharmaceutiques et des kits diagnostiques comprenant celles-ci, ainsi que leurs méthodes d'utilisation pour traiter les infections virales ou comme critère ou réactif d'analyse.

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