1,3-benzoxathiole derivatives, their use and their preparation

Details 1,3-benzoxathiole derivatives, their use and their preparation 1,3-benzoxathiole derivatives, their use and their preparation

C - Chemistry, Metallurgy

07

D

260/327.7

C07D 327/04 (2006.01) C07D 411/02 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1243323

ABSTRACT OF THE DISCLOSURE Compounds of formula (I): Image (I) in which: R1 represents a hydrogen atom, an alkyl group, a substituted alkyl group, a C2-C6 alkenyl group, an aryl group, a substituted aryl group or an alkoxycarbonyl group wherein the alkoxy part has from 1 to 6 carbon atoms: R2 represents a hydrogen atom, a C1-C6 alkyl group or a C3 or C4 alkenyl group; R3 represents a hydrogen atom or a C1-C6 alkyl group; R4 represents a hydroxy group, a C1-C21 aliphatic acyloxy group or a carbocyclic aryl carboxylic acyloxy group; R5 represents a C1-C12 alkyl group, a C1-C6 alkoxy group, a hydroxy group, a C1-C7 aliphatic acyloxy group or a carbocyclic aryl carboxylic acyloxy group; R6 represents a hydrogen atom, a C1-C6 alkyl group or a C1-C6 alkoxy group; and n is 0, 1, or 2: and pharmaceutically acceptable salts thereof are valuable in the treatment of circulatory disorders and allergies.

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