C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/179, 260/302
C07D 417/12 (2006.01) A61K 31/135 (2006.01) A61K 31/33 (2006.01) C07C 49/573 (2006.01) C07C 49/835 (2006.01) C07C 235/40 (2006.01) C07C 235/82 (2006.01) C07D 311/58 (2006.01) C07D 333/22 (2006.01) C07D 335/06 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2034546
Disclosed are 3-oxo-4-acyl or carbamyl-bicyclic aromatic and heterocyclic compounds of the formula: Image [wherein R is substituted phenyl, thienyl, phenylalkyl, (substituted) phenylamino, pyridylamino, pyrazolylamino, benzo- thiazolylamino, (substituted) thiazolylamino; X is CH2, C(CH3)2, O, S or N-CH3; n is 1 or 2; and Y is H or substituent] capable of inhibiting cyclo- oxygenase and lipoxygenase and are useful as antiallergy and antiinflammatory agents.
Ito Fumitaka
Kokura Toshihide
Nakane Masami
Nakao Kazunari
Limited Pfizer
Smart & Biggar
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