C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/231, 260/278
C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 209/34 (2006.01) C07D 209/96 (2006.01) C07D 401/14 (2006.01) C07D 407/14 (2006.01) C07D 409/14 (2006.01) C07D 471/10 (2006.01)
Patent
CA 2022486
1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-ones, a process for their preparation and their use as medicaments This invention relates to 1,3-dihydro-1- (pyridinylamino)-2H-indol-2-ones of the formula (see formula I) where R1, R2 and R3 are independently hydrogen, loweralkyl, aryl, arylloweralkyl or heteroarylloweralkyl selected from the group consisting of pyridinylmethyl, pyridinylethyl, thienylmethyl, thienylethyl; or R2 and R3 together form a cycloalkane ring of 4 to 6 carbons or a spiro-fused aryl cycloalkane or heterocycloalkyl selected from the group consisting of piperidine and tetrahydropyran; X and Y are independently hydrogen, halogen, hydroxy, loweralkyl, loweralkoxy, nitro, amino or trifluoromethyl; m and n are independently integers of 1 to 3, the pharmaceutically acceptable acid addition salts thereof and, where applicable the optical, geometrical and stereoisomers and racemic mixtures thereof and to a process for their preparation. The compounds of this invention display utility as analgesics, anticonvulsants, for enhancing memory and for the treatment of Alzheimer's disease.
Effland Richard Charles
Wettlaufer David Gordon
Aventis Holdings Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst-Roussel Pharmaceuticals Inc.
LandOfFree
1,3-dihydro-1-(pyridinylamino)-2h-indol-2-ones, a process... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,3-dihydro-1-(pyridinylamino)-2h-indol-2-ones, a process..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,3-dihydro-1-(pyridinylamino)-2h-indol-2-ones, a process... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1616060