1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)-7-...

Details 1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)-7-... 1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)-7-...

C - Chemistry, Metallurgy

07

D

260/276.2

C07D 491/048 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1300149

A B S T R A C T This invention relates to a new preparation process of the 1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)- 7 - hydroxy-furo - (3,4-c) - pyridine derivatives of the general formula : Image wherein, each of Al and A2 independently, represents various substituents consisting in reacting a 6-formyl-7- hydroxy-furo-(3,4-c)-pyridine derivative of the general formula : Image wherein Al and A2 have the above meanings with a slight excess of l-dimethylaminomethyl-vinylmagnesium bromide at the boil, in a non polar solvent such as tetrahydrofuran.

489219

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