1,3-dihydroisoindole derivatives

Details 1,3-dihydroisoindole derivatives 1,3-dihydroisoindole derivatives

C - Chemistry, Metallurgy

07

D

C07D 209/44 (2006.01) A61K 31/4035 (2006.01) A61P 35/00 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2697934

The invention relates to novel 1,3-dihydroisoindole derivatives of formula (I), in which R1 - R3 are defined as cited in claim 1. Said derivatives are HSP90 inhibitors and can be used to produce a medicament for treating diseases, in which the inhibition, regulation and/or modulation of HSP90 plays a part.

L'invention concerne de nouveaux dérivés de 1,3-dihydro-isoindole représentés par la formule (I) dans laquelle R1 - R3 ont la signification donnée dans la revendication (1). Ces dérivés sont des inhibiteurs de HSP90 et peuvent être employés pour la fabrication d'un médicament destiné au traitement de maladies dans lesquelles l'inhibition, la régulation et/ou la modulation de HSP90 joue un rôle.

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