1,3-dioxane derivatives, synthesis method therefor and...

C - Chemistry – Metallurgy – 07 – D

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C07D 319/06 (2006.01) A61K 7/46 (1995.01)

Patent

CA 2260851

Compounds with a 1,3-dioxane structure of general formula (I), wherein Z is pentyl or pent-2-enyl grouping (Z) or (E) and R is a hydrocarbon grouping, characterised in that they are prepared from apples or apple by-products, are disclosed. A method for synthesising said compounds by acetylising the corresponding 1,3-diol of general formula (II), wherein Z is as defined above, with an aldehyde of formula (a), wherein R is as defined above, is also disclosed. Furthermore, aromatic compositions containing the compounds with a 1,3-dioxane structure prepared according to said synthesis method, are disclosed.

L'invention concerne les composés de structure 1,3-dioxane de formule générale (I), dans laquelle Z est le groupement pentyle ou pent-2-ényle (Z) ou (E) et R est un groupement hydrocarboné, caractérisés en ce qu'ils sont obtenus à partir de la pomme ou des ses produits dérivés. L'invention se rapporte également à un procédé de synthèse de ces composés caractérisé en ce qu'il consiste en l'acétalisation du diol-1,3 correspondant de formule générale (II), dans laquelle Z est défini ci-dessus, par un aldéhyde de formule (a) dans laquelle R est défini précédemment. L'invention concerne enfin les compositions aromatiques contenant les composés de structure 1,3-dioxane obtenus selon le procédé de synthèse précité.

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