C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 205/04 (2006.01) A61K 31/397 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2534550
Compounds of formula Ia or Ib in free or salt form, wherein Ar, X1, X2, m, R1, Q, Y, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by CCR-3, for example an inflammatory or allergic condition, particularly an inflammatory or obstructive airways disease. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
L'invention concerne des composés de formule Ia ou Ib sous forme libre ou sous forme de sel, dans lesquelles Ar, X?1¿, X?2¿, m, R?1¿, Q, Y, R?2¿ et R?3¿ ont les significations indiquées dans la description, qui sont utiles pour le traitement d'états dont la médiation est assurée par le récepteur CCR3, par exemple une maladie inflammatoire ou obstructive des voies aériennes. L'invention concerne également des compositions pharmaceutiques qui contiennent lesdits composés ainsi qu'un procédé de préparation de ces derniers.
Fetherstonhaugh & Co.
Novartis Ag
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