1,3-disubstituted heteroaryl nmda/nr2b antagonists

Details 1,3-disubstituted heteroaryl nmda/nr2b antagonists 1,3-disubstituted heteroaryl nmda/nr2b antagonists

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) C07C 233/09 (2006.01) C07C 249/04 (2006.01) C07C 255/34 (2006.01) C07D 207/50 (2006.01) C07D 249/02 (2006.01) C07D 249/18 (2006.01) C07D 263/32 (2006.01) C07D 271/02 (2006.01) C07D 277/28 (2006.01) C07D 285/01 (2006.01) C07D 315/00 (2006.01)

Patent

CA 2575430

Compounds represented by Formula I: (wherein A, B, D, P, Q, R1, R2, R3, W and Y are described herein) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson~s disease, Alzheimer~s disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.

La présente invention concerne des composés représentés par la formule générale (I) ou certains de leurs sels pharmaceutiquement admis. Dans cette formule, les B, D, P, Q, R1, R2, R3, W et Y sont tels que décrits dans les spécifications. Ces composés, qui agissent comme antagonistes des NMDA/NR2B, conviennent au traitement d'états neurologiques tels que notamment la douleur, la maladie de Parkinson, la maladie d'Alzheimer, l'épilepsie, la dépression, l'anxiété, les lésions cérébrales ischémiques y-compris les accidents cérébro-vasculaires, et d'autres états.

Affiliated with

Also associated with

Rating

1,3-disubstituted heteroaryl nmda/nr2b antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,3-disubstituted heteroaryl nmda/nr2b antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,3-disubstituted heteroaryl nmda/nr2b antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1943585