1,3-disubstituted indole derivatives for use as ppar modulators

Details 1,3-disubstituted indole derivatives for use as ppar modulators 1,3-disubstituted indole derivatives for use as ppar modulators

C - Chemistry, Metallurgy

07

D

C07D 409/14 (2006.01) A61K 31/405 (2006.01) A61P 3/10 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2621474

Compounds are described that are active on PPARs, including pan-active compounds and compounds selective for any one or any two of PPAR.alpha., PPAR.gamma. and PPAR.delta.. Also describe are methods of use of the compounds in treating various diseases.

L'invention concerne des composés qui sont actifs sur les PPAR, y compris les composés ayant une activité sur pan et des composés sélectifs pour un ou deux quelconques de PPARa, PPAR? et PPARd. L'invention concerne également des procédés d'utilisation de ces composés dans le traitement de diverses maladies.

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