1-(3-mercapto-2-methylpropanoyl) prolyl amino acid...

Details 1-(3-mercapto-2-methylpropanoyl) prolyl amino acid... 1-(3-mercapto-2-methylpropanoyl) prolyl amino acid...

C - Chemistry, Metallurgy

07

D

530/5.06

C07D 207/14 (2006.01) A61K 31/40 (2006.01) C07D 207/16 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01)

Patent

CA 1288547

- 1 - Abstract of the Disclosure 1-(3-Mercapto-2-methylpropanoyl)prolyl amino acid derivatives of the formula Image wherein R represents a hydrogen atom, a lower alkyl group, a phenyl-lower alkyl group or a substituted phenyl-lower alkyl group, R1 represents a hydrogen atom, R4CO-, R5S-, or Image , R2 represents a hydrogen atom or a lower alkyl group, R3 represents a hydrogen atom, a phenyl group, a lower alkyl group, or a substituted lower alkyl group, or R2 and R3 form a heterocyclic ring together with the nitrogen and carbon atoms to which they are respectively bonded; salts of these compounds; compositions comprising these compounds or salts; and processes for preparing these com- pounds or salts. These compounds and salts have excellent antihypertensive activity.

331321

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