C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/422 (2006.01) A61P 3/00 (2006.01) C07D 263/32 (2006.01) C07D 471/04 (2006.01) C07F 5/02 (2006.01)
Patent
CA 2517307
The invention relates to 1,3-substituted cycloalkyl derivatives containing acidic, mainly heterocyclic groups, in addition to their physiologically compatible salts and physiologically functional derivatives. The invention relates to compounds of formula (I), in which the groups are defined as cited in the description, in addition to their physiologically compatible salts and to a method for their production. The compounds are suitable for treating and/or preventing disorders of the fatty acid metabolism and disorders of glucose utilisation in addition to disorders, in which insulin resistance plays a part.
L'invention concerne des dérivés de cycloalkyle 1,3-substitués contenant des groupes acides principalement hétérocycliques ainsi que leurs sels physiologiquement acceptables et des dérivés physiologiquement fonctionnels. La présente invention porte également sur des composés de formule (I), dans laquelle les groupes ont les significations indiquées, sur leurs sels physiologiquement acceptables et sur des procédés de préparation associés. Les composés de l'invention servent au traitement et/ou à la prévention de troubles du métabolisme des acides gras, de troubles de la transformation du glucose et de troubles où la résistance à l'insuline joue un rôle.
Falk Eugen
Glombik Heiner
Goerlitzer Jochen
Gretzke Dirk
Keil Stefanie
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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