1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulene derivatives as...

Details 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulene derivatives as... 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulene derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/55 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2659352

The invention relates to 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulene derivatives of formula (II), wherein the chirality is as depicted below, (II) and their use as orexin receptor antagonists.

Dérivés de 1,4,5,6,7,8-hexahydro-1,2,5-thaza-azulène de formule (II), dont la chiralité est telle que décrite ci-après, (II), et leur utilisation comme antagonistes de récepteur d'orexine.

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