1,4,5,6,7,8-hexahydroquinoline compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 215/02 (2006.01) C07D 215/14 (2006.01) C07D 215/18 (2006.01) C07D 215/24 (2006.01) C07D 215/36 (2006.01) C07D 215/54 (2006.01) C07D 221/04 (2006.01) C07D 311/74 (2006.01) C07D 311/94 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 409/10 (2006.01)

Patent

CA 1282411

Abstract Circulation-active dihydropyridines of the formula Image in which R1 is optionally substituted aryl or heterocyclic, R2 is H, NO2, CN, C1-C8-alkylsulphonyl, aryl or carboalkoxy, R3 is alkyl or aryl,, R4 is H or alkyl, X is C=O or a direct bond, and n is a number from 1 to 20, or physiologically acceptable salts thereof. A synthesis using morpholines or thiomorpholines is also disclosed.

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