1,4,8,11-tetraazacyclotetradecane derivatives as...

Details 1,4,8,11-tetraazacyclotetradecane derivatives as... 1,4,8,11-tetraazacyclotetradecane derivatives as...

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07D 257/02 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2361115

1,4,8,11-Tetraazacyclotetradecane which is chemically linked to from one to four nitroimidazol groups provides an effective radiodiagnostic agent for determining tissue hypoxia and radioresistance of tumor tissue.

Du 1,4,8,11-tétraazaclyclotétradécane qui est chimiquement lié à un ou plusieurs groupes nitroimidazole dont le nombre peut varier entre un et quatre constitue un agent de radiodiagnostic efficace permettant de déterminer l'hypoxie tissulaire et la radiorésistance de tissus tumoraux.

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