1,4-aminoalkylamino-9h-thioxanthen-9-ones

Details 1,4-aminoalkylamino-9h-thioxanthen-9-ones 1,4-aminoalkylamino-9h-thioxanthen-9-ones

C - Chemistry, Metallurgy

07

D

167/242, 260/328

C07D 335/16 (2006.01) A61K 31/38 (2006.01)

Patent

CA 1241335

ABSTRACT 1,4-Aminoalkylamino-9H-thioxanthen-9-ones of the following general formula have antlmicrobial activity and activity against leukemic cells. Methods for their preparation, use and pharmaceutical compositions are described: Image (I) wherein R5, R6, R7 and R8, independently, are H, -OH or C1-4alkoxy; A and B, independently, are C2-5alkylene or OH- substituted C2-5alkylene, and R1, R2, R3 and R4, independently, are H, C1-4alkyl or OH-substituted C1-4alkyl.

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