1-(4-aminophenyl)-2-piperidinopropanone derivatives,...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/18 (2006.01) A61K 31/445 (2006.01) C07D 295/108 (2006.01)

Patent

CA 2028764

ABSTRACT The present invention relates to 1-(4-amino- phenyl)-2-piperidinopropanone derivatives which are selected from (a) the compounds corresponding to the general formula Image where R is H or CH3CO, A is H or Cl, B is H or Cl and Z is C1-C4-alkyl; and (b) their addition salts, These products are u ed as cardiovascular agents. In particular, the compounds of the formula I where R = H or CH3CO, A = B = Cl and Z = CH3, and their addition salts, are especially very worthwhile as vasodilators. Fig. none

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