1 , 4 and 1 , 5-disubstituted indole derivatives for use as...

Details 1 , 4 and 1 , 5-disubstituted indole derivatives for use as... 1 , 4 and 1 , 5-disubstituted indole derivatives for use as...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/405 (2006.01) A61P 3/10 (2006.01) C07D 209/08 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2621275

Compounds are described that are active on at least one of PPAR.alpha., PPAR.delta., and PPAR.gamma., which are useful for therapeutic and/or prophylactic methods involving modulation of at least one of PPAR.alpha., PPAR.delta., and PPAR.gamma. . wherein R1 is selected from the group consisting of -C(O)OR18R19, and a carboxylic acid isostere.

L'invention concerne des composés qui sont actifs sur au moins un parmi les PPAR.alpha., PPARd, et PPAR?, que l'on utilise dans des procédés thérapeutiques et/ou prophylactiques impliquant la modulation d'au moins un parmi les PPAR.alpha., PPARd, et PPAR?.

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