1,4-benzodiazepin-2-on derivatives

Details 1,4-benzodiazepin-2-on derivatives 1,4-benzodiazepin-2-on derivatives

C - Chemistry, Metallurgy

07

D

C07D 243/14 (2006.01) A61K 31/5513 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2752739

The present invention relates to a compound represented by a formula (I): wherein R1 represents a halogen atom or the like; R2 represents a hydrogen atom or the like; R3 and R4 each independently represents lower alkyl; R5 represents phenyl or the like; R6 represents a halogen atom or the like; m is an integer of from 0 to 2; p is an integer of from 1 to 4; and q is an integer of from 1 to 5 as an inhibitor of DGAT1 and its use for the treatment of hyperlipidemia etc.

La présente invention concerne un composé représenté par la formule (I) : dans laquelle R1 représente un atome d'halogène ou similaire; R2 représente un atome d'hydrogène ou similaire; R3 et R4 représentent chacun indépendamment un groupe alkyle inférieur; R5 représente un groupe phényle ou similaire; R6 représente un atome d'halogène ou similaire; m est un nombre entier allant de 0 à 2; p est un nombre entier allant de 1 à 4; et q est un nombre entier allant de 1 à 5, comme inhibiteur de DGAT1 ainsi que son utilisation pour le traitement de l'hyperlipidémie, etc.

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