1,4-benzothiazepine-1,1-dioxide derivatives substituted by...

Details 1,4-benzothiazepine-1,1-dioxide derivatives substituted by... 1,4-benzothiazepine-1,1-dioxide derivatives substituted by...

C - Chemistry, Metallurgy

07

H

C07H 15/26 (2006.01) A61K 31/554 (2006.01) A61K 31/7052 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) C07D 281/10 (2006.01) C07H 15/18 (2006.01)

Patent

CA 2369070

1,4-Benzothiazepine-1,1-dioxide derivates, process for their preparation, pharmaceuticals comprising these compounds, and their use The invention relates to substituted 1,4-benzothiazepine-1,1-dioxide derivates and their acid addition salts. 1,4-Benzothiazepine-1,1-dioxide derivates of the formula I, Image in which R1, R2, R3 and Z have the meanings indicated, and the physiologically tolerable salts and physiologically functional derivatives and also processes for their preparation are described. The compounds are suitable, for example, as hypolipidemics.

L'invention concerne des dérivés de 1,4-benzothiazépin-1,1-dioxyde substitués et leurs sels d'addition d'acide. L'invention concerne également des dérivés de 1,4-benzothiazépin-1,1-dioxyde de la formule (I) où R<1>, R<2>, R<3> et Z ont la signification donnée ; leurs sels physiologiquement compatibles, leurs dérivés physiologiquement fonctionnels ainsi que leur procédé de production. Ces composés conviennent, par exemple, comme hypolipidémiants.

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