1,4-benzoxazine and 1,4-benzothiazine derivatives and...

Details 1,4-benzoxazine and 1,4-benzothiazine derivatives and... 1,4-benzoxazine and 1,4-benzothiazine derivatives and...

C - Chemistry, Metallurgy

07

D

167/211, 260/243

C07D 265/36 (2006.01) A61K 31/535 (2006.01) C07D 279/16 (2006.01) C07D 413/06 (2006.01) C07D 471/10 (2006.01)

Patent

CA 1327575

A B S T R A C T The present invention relates to new compounds having the following formula (I) Image (I) wherein X represents -O- or -S-; each of R and R1, independently, is hydrogen, halogen, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, amino, nitro or trihalo-C1-C6al kyl; each of R2 and R3, independently, is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl or phenyl-C1C6 alkyl; or R3 and R3, taken together with the nitrogen atom to which they are linked, form an unsubstituted or substituted, 6-memebered, saturated, heteromonocyclic ring optionally containing a further heteroatom chosen from oxygen, sulphur and nitrogen; each of R4 and R5, independently, is hydrogen, halogen, nitro, amino or trihalo-C1-C6 alkyl, and the pharmaceutically acceptable salts thereof. The compounds of the invention are useful in therapy as major tranquilizers e.g, in the management of psychotic disorders.

590955

Affiliated with

Also associated with

Rating

1,4-benzoxazine and 1,4-benzothiazine derivatives and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,4-benzoxazine and 1,4-benzothiazine derivatives and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-benzoxazine and 1,4-benzothiazine derivatives and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1171398