1,4-benzoxazine derivative, pharmaceutical composition...

C - Chemistry – Metallurgy – 07 – D

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C07D 265/36 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2165503

A 1,4-benzoxazine derivative of the following formula (I): Image (I) or a pharmaceutically acceptable salt thereof is disclosed. The compound of the present invention is useful as a medica- ment for preventing or treating disorders induced by intracel- lular acidosis during myocardial ischemia, such as cardiac dysfunction, myocardial necrosis, arrhythmia, reperfusion injury, and the like, which are observed in ischemic heart diseases (e.g. myocardial infarction, angina pectoris, etc.).

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