1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives

Details 1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives 1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives

C - Chemistry, Metallurgy

07

D

C07D 295/18 (2006.01) A61K 31/496 (2006.01) A61P 29/00 (2006.01) C07D 207/14 (2006.01) C07D 207/16 (2006.01) C07D 207/28 (2006.01) C07D 211/48 (2006.01) C07D 211/58 (2006.01) C07D 215/38 (2006.01) C07D 233/74 (2006.01) C07D 295/185 (2006.01)

Patent

CA 2502633

A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, wherein the symbols have meaning as defined, which are antagonists of CCR-1 and which find use pharmaceutically for treatment of diseases and conditions in which CCR-1 is implicated, e.g. inflammatory diseases.

L'invention concerne un composé de formule I, un sel ou un ester pharmaceutiquement acceptable de celui-ci, dans laquelle les symboles sont tels que définis dans le descriptif, et représentent des antagonistes de CCR-1, que l'on utilise au niveau pharmaceutique pour traiter des maladies et des états impliquant le CCR-1, par exemple des maladies inflammatoires.

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