1-4-bis(substituted-amino)-5,8- dihydroxyanthraquinones and...

C - Chemistry – Metallurgy – 07 – D

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260/236.1

C07D 263/04 (2006.01) C07D 263/16 (2006.01) C07D 263/52 (2006.01) C07D 265/06 (2006.01) C07D 265/08 (2006.01) C07D 265/32 (2006.01) C07D 267/10 (2006.01) C07D 413/00 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1194868

TITLE: NOVEL 1,4-BIS(SUBSTITUTED-AMINO)- -5,8-DIHYDROXYANTHRAQUINONES AND LEUCO BASES THEREOF ABSTRACT OF THE DISCLOSURE This disclosure describes novel 1,4-bis(substi- tuted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof, useful as chelating agents and for inhibiting the growth of transplanted mouse tumors. This disclosure also describes compositions of matter useful as inhib- itors of transplanted mouse tumor growth and the method of inducing the regression and/or palliation of leukemia and related cancers in mammals therewith.

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