1,4-dihydropyridine carboxylic acid ester derivatives,...

Details 1,4-dihydropyridine carboxylic acid ester derivatives,... 1,4-dihydropyridine carboxylic acid ester derivatives,...

C - Chemistry, Metallurgy

07

D

167/225, 260/277

C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 211/90 (2006.01)

Patent

CA 1334591

Compounds are described of the formula Image (I) wherein R1 is a nitro or trifluoromethyl group; R2 is a C1-C6 alkyl group; R3 is a pyridyl or pyridyl N-oxide group which may be substituted with halogen, hydroxyl, haloalkyl, C1-C6 alkoxy or C1-C6 alkyl and further may be fused with a benzene or naphthalene ring, said ring being optionally substituted with C1-C6 alkyl, C1-C6 alkoxy, halogen or haloalkyl, and a pharmaceutically acceptable acid addition salt thereof. The compounds of the formula (I) are of vasodilating and blood pressure lowering activities and thus may be useful for the treatment of cardiac diseases, cerebrovascular diseases and hypertension.

538977

Affiliated with

Also associated with

Rating

1,4-dihydropyridine carboxylic acid ester derivatives,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,4-dihydropyridine carboxylic acid ester derivatives,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-dihydropyridine carboxylic acid ester derivatives,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1245825