1,4-dihydropyridine compounds linked in the c-3 position,...

C - Chemistry – Metallurgy – 07 – D

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260/246.3, 260/2

C07D 211/90 (2006.01) C07D 401/00 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1179342

ABSTRACT OF THE DISCLOSURE The invention relates to dimeri- 1,4-dihydropyridine compounds of formula X Image I Compounds of the invention include, for example, henanediyl 1,6-bis-[2,6- dimethyl-5-methocycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-4-carboxylate] and bexanediyl 1,6-bis-[2,6-dimethyl-5-methoxycarbonyl-4-(2-nitrophenyl)-1,4- dihydropyridine-4-carboxylate]. The compounds display valuable circulation influencing effects and can be used as antihypertensive agents, as vasodilators, as cerebral therapeutic agents and as coronary therapeutic agents.

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