1,4-dihydropyridine derivatives useful for the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/80 (2006.01) C07D 211/90 (2006.01) C07D 215/54 (2006.01) C07D 401/02 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 491/052 (2006.01)

Patent

CA 1267416

ABSTRACT The present invention is novel 1,4-dihydro- pyridine derivatives having activity as calcium antagonists useful for the treatment of cardiovascular disorders. More particularly, the invention includes preferred compounds which in addition to the useful- ness associated with calcium antagonism also exhibit positive inotropic effect without the usual accom- panying negative inotropic effect. Thus, the pre- ferred compounds additionally provide beneficial increased myocardial activity.

510582

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