1,4-dihydropyridines

Details 1,4-dihydropyridines 1,4-dihydropyridines

C - Chemistry, Metallurgy

07

D

260/271, 260/277

C07D 401/06 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1329600

- 1 - ABSTRACT 1,4-DIHYDROPYRIDINES The invention concerns compounds of formula Image (I) or salts thereof; wherein: .alpha. and .beta. together represent a bond and additionally when B is an electron withdrawing group can also represent OH and .beta. can represent hydrogen; Ar is an optionally substituted aryl radical; R represents hydrogen or an optionally substituted alkyl or aralkyl group; R1 and R2 are the same or different and are selected from hydrogen and saturated or unsaturated, cyclic or acyclic aliphatic hydrocarbon residues optionally substituted by one or more groups selected from halogen, OH, carboxy, CN, alkoxy, alkylthio, aryloxy, alkoxycarbonyl, amino, substituted amino, and optionally substituted aryl; A represents a group of formula -XR3 wherein X is a group of formula -(CHR6)p-Y-(CHR7)q- in which formula : Y represents -O-, -S-, NR8 or a direct bond, p and q each represent 0, 1 or 2 R6, R7 and R8 independently represent hydrogen or lower alkyl and R3 is an optionally substituted nitrogen ring heteroaryl radical optionally containing other ring heteroatoms selected from oxygen, nitrogen or sulphur; B represents haloalkyl, optionally substituted phenyl, -CN, -CHO, -CH(Olower- alkyl)2 or -CH2OH.

528568

Affiliated with

Also associated with

Rating

1,4-dihydropyridines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,4-dihydropyridines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-dihydropyridines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1325852