1,4-dihydropyridines, a process for their preparation and...

Details 1,4-dihydropyridines, a process for their preparation and... 1,4-dihydropyridines, a process for their preparation and...

C - Chemistry, Metallurgy

07

D

167/231, 260/279

C07D 405/10 (2006.01) A61K 31/44 (2006.01) C07D 211/90 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 1306261

ABREGE DESCRIPTIF 1,4-DIHYDROPYRIDINES, LEUR PROCEDE DE PREPARATION ET LEUR APPLICATION COMME MEDICAMENTS. L'invention concerne de nouvelles 1,4-dihydropyridines de formule générale (III) Image (III) dans laquelle : - R1 représente un groupe alkyle C1-C4, linéaire ou ramifié, substitué ou non, tel que méthyle, éthyle, propyle, isopropyle, butyle, isobutyle, méthoxyéthyle, - R2 représente un radical C1-C2 tel que méthyle, formyle, éthyle, - R3 représente un atome d'hydrogène, ou un noyau aromatique, substitué ou non, tel que 2-, 3-, ou 4-picolyle, thiophényle, 4-fluorobenzyle. Ces composés sont doués de propriétés antagonistes du calcium, et utiles dans le traitement des troubles cardiovasculaires.

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