1,4-dihydropyridines with diphenylpiperidylester group

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/435 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/455 (2006.01) C07D 211/00 (2006.01) C07D 211/14 (2006.01) C07D 211/22 (2006.01) C07D 211/82 (2006.01) C07D 211/90 (2006.01) C07D 307/36 (2006.01) C07D 401/00 (2006.01) C07D 401/14 (2006.01) C07D 405/00 (2006.01) C07D 405/14 (2006.01) C07D 409/00 (2006.01) C07D 409/14 (2006.01) C07D 413/00 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1291137

Abstract New diaryl compounds of the general formula I, (I) Image and their pharmaceutically acceptable salts are useful as vasodi- lators and coronary therapeutics. In a preferred compound R1, R2, and R3 are methyl, Ar is 3-nitrophenyl, A is -CH2CH2CH2 and R6, R7, R8 and R9 are each hydrogen. Processes for preparing the diaryl compounds of general formula I and pharmaceutical composi- tions containing them are also disclosed.

491694

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