1,4-disubstituted isoquinilone derivatives as raf-kinase...

Details 1,4-disubstituted isoquinilone derivatives as raf-kinase... 1,4-disubstituted isoquinilone derivatives as raf-kinase...

C - Chemistry, Metallurgy

07

D

C07D 217/22 (2006.01) A61K 31/4725 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2538855

This invention relates to compounds of formula (I) wherein the variable substituents are described herein. The compounds are useful for the treatment of conditions and diseases characterized by an aberrant MAP kinase signaling pathway, such as cancer.

La présente invention a trait à des composés de formule (I), dans laquelle les substituants sont tels que définis dans la description. Les composés sont utiles pour le traitement de conditions et de maladies caractérisées par une voie de signalisation aberrante de la protéine kinase associée aux membranes, telles que le cancer.

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