C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 339/00 (2006.01) A61K 31/385 (2006.01) A61P 3/04 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) C07D 339/08 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2374775
The invention is directed to 1,4-dithiin- and 1,4-dithiepin- 1,1,4,4-tetroxide derivatives useful as galanin receptor antagonists for treating disorders of the central nervous system. Pharmaceutical compositions comprising the compounds of the present invention and methods of treating conditions such as an eating disorder, obesity, bulimia nervosa, anorexia nervosa, binge eating, diabetes, dyslipidemia, hypertension, memory loss, sleep disturbances, pain, depression, anxiety, Alzheimer's disease, senile dementia, cerebral hemorrhage, or diarrhea are also described.
L'invention concerne des dérivés de 1,4-dithiine et de 1,4-dithiépin-1,1,4,4-tétroxyde utilisés comme antagonistes du récepteur de galanine, ces dérivés permettant par ailleurs de traiter des troubles du système nerveux central. Cette invention concerne également des compositions pharmaceutiques renfermant les composés de la présente invention, ainsi que des méthodes de traitement de pathologies comme les troubles de l'alimentation, l'obésité, la boulimie et l'anorexie mentales, les épisodes d'alimentation excessive, le diabète, la dyslipidémie, l'hypertension, l'amnésie, les troubles du sommeil, la douleur, la dépression, l'anxiété, la maladie d'Alzheimer, la démence sénile, l'hémorragie cérébrale, ou la diarrhée.
Lee Daniel H. S.
Reitz Allen B.
Scott Malcolm K.
Wang Hoau-Yan
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
LandOfFree
1,4-dithiin and 1,4-dithiepin-1,1,4,4, tetroxide derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,4-dithiin and 1,4-dithiepin-1,1,4,4, tetroxide derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,4-dithiin and 1,4-dithiepin-1,1,4,4, tetroxide derivatives... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1537510