C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 17/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2585660
The invention relates to 1,4-substituted pyrazolopyrimidine compounds of the formula (I), pharmaceuticals comprising a 1,4-substituted pyrazolopyrimidine compound, the use of a 1,4-substituted pyrazolopyrimidine compound in the treatment or the use thereof in the manufacture of a pharmaceutical formulation for the treatment of a disease that depends on inadequate activity of a protein kinase, methods of treatment comprising administering a 1,4- substituted pyrazolopyrimidine compound, methods for the manufacture of a novel compound of that class, and novel intermediates and partial steps for their synthesis.
La présente invention a pour objet des dérivés 1,4-substitués de pyrazolopyrimidines, de formule (I), des produits pharmaceutiques incluant un dérivé de ce type, l'emploi d'un dérivé de ce type dans le traitement d'une maladie due à l~activité non conforme d'une protéine kinase, l'emploi d'un dérivé de ce type dans l'élaboration d'une formule pharmaceutique destinée au traitement d~une telle maladie, des méthodes de traitement comprenant l~administration d~un dérivé de ce type, des méthodes de synthèse d~un nouveau composé appartenant à cette classe de molécules, ainsi que de nouveaux composés et étapes intermédiaires pour ces synthèses.
Furet Pascal
Holzer Philipp
Imbach Patricia
Schmiedeberg Niko
Fetherstonhaugh & Co.
Novartis Ag
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