1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxyla...

Details 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxyla... 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxyla...

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/4245 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2488117

The present invention encompasses compounds of Formula I: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

L'invention concerne des composés représentés par la formule I ainsi que leurs sels et leurs hydrates pharmaceutiquement acceptables. Ces composés sont utiles pour le traitement de maladies et d'affections d'origine immunologique, telles que le rejet de transplantation de la moelle osseuse, d'un organe ou d'un tissu. L'invention concerne également des compositions pharmaceutiques et les méthodes d'utilisation desdites compositions.

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