1,5-benzoxazepine derivatives

Details 1,5-benzoxazepine derivatives 1,5-benzoxazepine derivatives

C - Chemistry, Metallurgy

07

D

167/209, 260/238

C07D 267/12 (2006.01) A61K 31/55 (2006.01) C07D 211/22 (2006.01) C07D 211/34 (2006.01) C07D 213/55 (2006.01) C07D 267/14 (2006.01) C07D 309/08 (2006.01) C07D 335/02 (2006.01) C07D 413/12 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1247611

Abstract Novel condensed, seven-membered ring compounds of the formula Image [wherein R1 and R2 are independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or both jointly form tri- or tetramethylene; R3 is hydrogen, optionally substituted lower alkyl or optionally substituted aralkyl; R4 is hydrogen, optionally substituted alkyl, optionally substituted aralkyl or optionally substituted cycloalkylalkyl; Y is a carboxyl group which may be esterified or amidated; m is 1 or 2] and salts thereof. These compounds and salts thereof exhibits inhibitory activity on angiotensin converting enzyme and so forth, and are of value as an agent for diagnosis, prevention and treatment of circulatory diseases (e.g. hypertension, cardiopathy, cerebral apoploxy).

460698

Affiliated with

Also associated with

Rating

1,5-benzoxazepine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,5-benzoxazepine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,5-benzoxazepine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1272016