C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/266.1
C07D 401/14 (2006.01) C07D 231/22 (2006.01) C07D 401/12 (2006.01) C07D 403/00 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 498/04 (2006.01)
Patent
CA 1208643
41 ABSTRACT 1,5-Diphenylpyrazo1in-3-one compounds method for preparing them, and pharmaceutical compositions containing these compounds New 1,5-diphenylpyrazolin-3-one compounds and a method of preparing them are described. The compounds have the general formula I Image I where R1 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxy, trifluoromethyl or lower alkanoyloxy radical, R2 is a hydrogen or halogen atom, or a lower alkyl, or lower alkoxy radical, or R1 and R2 are bonded to adjacent carbon atoms and together denote a methylenedioxy or ethyl- enedioxy radical, R3 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxy, trifluoromethyl or lower alkanoyloxy radical, R4 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy radical, or R3 and R4 are bonded to adjacent carbon atoms and together denote a methyl- 42 enedioxy or ethylenedioxy radical, Z is an alkylene radical with 2 to 6 carbon atoms and R5 is an optionally substituted pyridyl radical, a thienyl radical or an optionally substituted phenyl radical. The compounds have pharmacological properties, for example antiallergic properties.
409072
Heinemann Henning
Jasserand Daniel
Milkowski Wolfgang
Yavordios Dimitri
Zeugner Horst
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Solvay Pharmaceuticals Gmbh
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