1,5-diphenylpyrazoles ii as hsp90 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/44 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2652393

Novel 1,5-diphenylpyrazole derivatives of formula (I), where R1, R6 have the meanings given in claim 1 are HSP90 inhibitors and can be used for production of a medicament for treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

L'invention concerne de nouveaux dérivés de 1,5-diphénylpyrazole de formule (I) dans laquelle R1 àR6 ont les significations indiquées dans la revendication 1. Ces nouveaux dérivés sont des inhibiteurs de HSP90 et peuvent être utilisés pour produire un médicament destiné à traiter des maladies dans lesquelles l'inhibition, la régulation et/ou la modulation de HSP90 jouent un rôle.

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