1,5-distributed pyrrolid-2-one derivatives for use as ep4...

Details 1,5-distributed pyrrolid-2-one derivatives for use as ep4... 1,5-distributed pyrrolid-2-one derivatives for use as ep4...

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/4015 (2006.01) A61K 31/41 (2006.01) A61K 45/06 (2006.01) A61P 27/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2488001

This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors of formula (I), their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of the patient.

La présente invention concerne des agonistes sélectifs puissants du sous-type EP¿4? de récepteurs E2 de prostaglandine de formule I, leur utilisation ou une préparation de ceux-ci utilisée dans le cadre du traitement du glaucome et d'autres pathologies qui sont liées à une pression intra-oculaire élevée dans l'oeil d'un patient.

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