1,5-naphthyridine azolidinones having cdk1 antiproliferative...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2583192

The present invention relates to 1,5-Naphthyridine azolidinones of the formula (I) to processes for the manufacture of said compounds, as well as medicaments containing them. These compounds are inhibitors of CDK1 and show anti prol if erative activity. They are therefore useful as anti-cancer agents.

L'invention concerne des 1,5-naphthyridine azolidinones de formule (I), des procédés relatifs à la fabrication de ces composés, et des médicaments qui contiennent les composés en question. Les composés considérés sont des inhibiteurs de CDK1 et ont un effet antiproliférant. Ils sont donc utiles comme anticancéreux.

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