1,6,7,8-tetrahydro-4-oxo-4h-pyrido (1,2-a)...

C - Chemistry – Metallurgy – 07 – D

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260/242.01

C07D 471/04 (2006.01)

Patent

CA 1054597

Abstract Compounds, having useful antidepressant activity, have the structure Image or a pharmaceutically acceptable salt thereof, wherein R1 is alkyl or aryl; R2 is hydrogen or alkyl; R3 is hydrogen, halogen, alkyl or aryl; and R4 is alkyl; where- in alkyl and alkoxy refer to groups having 1 to 6 carbon atoms and aryl refers to phenyl or phenyl substituted with one or two alkyl, alkoxy, halogen or trifluoromethyl groups.

233738

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