C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/208, 260/273
C07D 471/04 (2006.01) A61K 31/435 (2006.01) C07D 213/80 (2006.01)
Patent
CA 1263118
ABSTRACT 1,6-Napthyridine derivatives, processes for the prep- aration thereof and pharmaceutical compositions containing them The present invention provides 1,6-naphthyridine derivatives of the general formula:- Image (I) wherein R1 is an unsubstituted or substituted aromatic or heteroaromatic ring, R2 is a straight-chained or branched alkyl radical containing up to 4 carbon atoms or a benzyl radical, R3 is a hydrogen atom, a straight chained or branched alkyl radical or an alkoxycarbonyl radical containing up to 4 carbon atoms, R4 is a straight-chained or branched alkyl radical containing up to 4 carbon atoms and R5 is a carboxyl group or a straight-chained, branched or cyclic alkoxycarbonyl radical which contains up to 17 carbon atoms and option- ally also contains an oxygen, sulphur or nitrogen atom as well as the pharmacologically acceptable salts thereof The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them.
489290
Fritschi Edgar
Hartenstein Johannes
Kleinschroth Jurgen
Mannhardt Karl
Osswald Hartmut
Nippon Chemiphar Co. Ltd.
Smart & Biggar
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