1,7-dihydro-pyrrolo ¬3,4-e| ¬1,4|diazepin- 2(1h)-one...

C - Chemistry – Metallurgy – 07 – D

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260/239.5

C07D 487/04 (2006.01) C07D 207/34 (2006.01)

Patent

CA 1178583

ABSTRACT 1,7-Dihydro-pyrrolo[3,4-e][1,4]diazepin-2(1H)-ones of the formula Image wherein R is lower alkyl, R1 stands for hydrogen, methyl, ethyl or phenyl, R2 is hydrogen or lower alkyl and R3 is hydrogen; chloro, fluoro, bromo, trifluoromethyl or methoxy are described with anticonvulsant and anti-anxiety activity. Also described is the process for preparing the above compounds and pharmaceutical preparations containing them.

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