C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 471/06 (2006.01) C07D 487/04 (2006.01) C07D 487/06 (2006.01) C07D 498/04 (2006.01) C07D 498/06 (2006.01) C07D 513/04 (2006.01) C07D 513/06 (2006.01)
Patent
CA 2076553
Abstract of the Disclosure Pharmacologically active compounds corresponding to the formula I Image I which can be mono- or disubstituted in the phenyl ring and in which R3 denotes hydrogen, lower alkyl which can optionally be substituted by hydroxyl, lower alkenyl, C3-C6-cycloalkyl, C4-C7-cycloalkylalkyl or a phenyl or phenyl-lower alkyl group which is optionally substituted in the phenyl ring, R4 denotes hydrogen, alkyl having 1-7 carbon atoms, which can optionally be substituted by hydroxyl, C3-C7-alkenyl, C3-C6-cycloalkyl, C4-C7-cycloalkylalkyl or a phenyl or phenyl-lower alkyl group which is optionally substituted in the phenyl ring, A denotes an alkylene chain having 1-2 carbon atoms, which is optionally substituted by lower alkyl, or denotes a bond, oxygen or sulfur, Z denotes an alkylene chain having 2-4 carbon atoms, which is optionally substituted by lower alkyl or hydroxyl, B denotes nitrogen or the CH group, R5 denotes an optionally substituted pyridyl or phenyl radical, and D represents a bond or, if B denotes the CH group and R5 denotes an optionally substituted phenyl radical, D can also represent a CO group, and their acid addition salts and/or S-mono- or dioxides of sulfur-containing compounds of the formula I are described, together with processes and intermediates for their preparation.
Cottin Michel
Demonchaux Patrice
Dupassieux Pierre
Floc'h Francois
Jasserand Daniel
Kali-Chemie Pharma Gmbh
Swabey Ogilvy Renault
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