1,8-annelated quinoline derivatives substituted with...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/06 (2006.01) A61K 31/47 (2006.01) A61P 35/00 (2006.01) C07D 498/06 (2006.01)

Patent

CA 2469275

This invention comprises the novel compounds of formula (I) wherein r, s, A, X, Y1, Y2, R1, R2, R3, and R4 have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine.

L'invention concerne de nouveaux composés ayant la formule (I) dans laquelle r, s, A, X, Y<sb>1</sb>, Y<sb>2</sb>, R<sb>1</sb>, R<sb>2</sb>, R<sb>3</sb> et R<sb>4</sb> ont des sens définis, qui présentent une activité d'inhibition de farnésyl transférase, ainsi que leurs préparations, les compositions les contenant et leur utilisation en tant que médicaments.

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