C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61K 31/44 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2461132
The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C-R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8- naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
La présente invention concerne d'une façon générale des dérivés de naphttyridine représentés par la formule (I) dans laquelle U, X, Y ou Z est azote , les autres étant C-R, R est hydrogène ou un substituant. Cette invention concerne plus particulièrement des dérivés 1,8-naphtyridine et des compositions pharmaceutiques contenant ces dérivés. Des techniques de cette invention consistent à administrer un dérivé de naphtyridine de l'invention de façon à traiter le diabète et des pathologies associées.
Bullock William H.
Gunn David E.
Li Tindy
Liang Sidney X.
Liu Donglei
Bayer Pharmaceuticals Corporation
Borden Ladner Gervais Llp
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