C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/289, 260/277
C07D 401/04 (2006.01) C07D 207/263 (2006.01) C07D 215/40 (2006.01)
Patent
CA 1156235
ABSTRACT The compound of formula (I) Image (I) and acid addition salts thereof are of value in medicine in the treatment or prophylaxis of pain, inflammation or fever. The compound and its salts may be administered alone or as a pharmaceutical formulation. The compound may be prepared by methods analogous to those known in the art or, for example, by cyclisation of a 4-halo-N-(8-quinelyl)butyramide in the presence of aqueous sodium hydroxide and a phase transfer catalyst such as triethylbenzyl ammonium chloride.
365722
Hodgson Gordon L.
Shumaker Thomas K.
Swabey Mitchell
Wellcome Foundation Limited (the)
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